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Histone H2B Polyclonal Antibody, 100ul[BT-AP09962] Peripheral Blood Separation Tube plays crucial roles in tissue

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Histone H2B Polyclonal Antibody, 100ul[BT-AP09962] Peripheral Blood Separation Tube plays crucial roles in tissueHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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Description

plays crucial roles in tissue growth and repair

The tumor suppressor function of PP32 has been localized to a 25 amino acid region that is divergent between PP32 and acidic nuclear phosphoprotein 32 family member C encoded by ANP32C

Transcripts at this locus may also act directly as functional RNAs to recruit transcriptional regulators to the promoter of MYCN and stimulate transcription of this oncogene

The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues

and in leukocytes and certain cancer cells

Histone H2B Polyclonal Antibody, 100ul[BT-AP09962] Peripheral Blood Separation Tube plays crucial roles in tissueHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.

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