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ATS20 Polyclonal Antibody, 20ul Cryopreservation Expression of this gene is

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ATS20 Polyclonal Antibody, 20ul Cryopreservation Expression of this gene isThe protein encoded by this gene is a member of the ADAMTS family of zinc dependent proteases. The encoded protein has a signal peptide that is cleaved to release the mature peptide, which is secreted and found in the extracellular matrix. This protein may be involved in tissue remodeling.

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Description

Expression of this gene is induced by gamma interferon| and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome

While this locus itself is conserved among various species| the paralogs are found only in the genus Homo| and not in the genomes of non-human great apes

This gene encodes the enzyme responsible for the excision of 8-oxoguanine

Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10)

They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA| and a second domain which interacts with the rest of the tRNA structure

ATS20 Polyclonal Antibody, 20ul Cryopreservation Expression of this gene isThe protein encoded by this gene is a member of the ADAMTS family of zinc dependent proteases. The encoded protein has a signal peptide that is cleaved to release the mature peptide, which is secreted and found in the extracellular matrix. This protein may be involved in tissue remodeling.

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