Integrin alphaIIb Rabbit Polyclonal Antibody, 50ul High Speed Micro-Centrifuges VCAN is a member of

VCAN is a member of the aggrecan/versican proteoglycan family

Multiple transcript v

The protein encoded by this gene is a caspase-3 substrate that plays a role in regulating microfilament and cell shape changes during apoptosis

Binds RAB11A that has been activated by GTP binding

with a pseudogene located on 7q31-qter

Integrin alphaIIb Rabbit Polyclonal Antibody, 50ul High Speed Micro-Centrifuges VCAN is a member ofThis gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha IIb beta 3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system by mediating platelet aggregation. Mutations in this gene are associated with platelet type bleeding