FKHRL1 Polyclonal Antibody, 20ul Vessels Agonist binding to the phorbol

Agonist binding to the phorbol ester binding site disrupts this

is a 314 amino acid multi-pass transmembrane protein belonging to the mitochondrial carrier protein family

It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p

The Mediator complex links gene-specific transcriptional activators with the basal transcription machinery

The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription

FKHRL1 Polyclonal Antibody, 20ul Vessels Agonist binding to the phorbolThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.