GEMI8 Polyclonal Antibody, 20ul Biomatrix Maximize your lab efficiency with

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Multiple EGF like domains 8 encoded by MEGF8 is a single-pass type I membrane protein of unknown function that contains several EGF-like domains

This protein binds both the calcium uptake pump SERCA2B and the carbohydrate-binding chaperone calnexin| and it appears to play a role in calcium homeostasis in the ER

This gene is mapped to the chemokine receptor gene cluster region

Alpers-Huttenlocher syndrome (AHS)

GEMI8 Polyclonal Antibody, 20ul Biomatrix Maximize your lab efficiency withThe protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6 GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.