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KPCD3 Polyclonal Antibody, 100ul Drug Development and Evaluation processing 5' and 3' ends

SKU: 50270248644

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DKK108.00 DKK148.00

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KPCD3 Polyclonal Antibody, 100ul Drug Development and Evaluation processing 5' and 3' endsThis gene belongs to the multigene protein kinase D family of serine threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N terminal regulatory domain comprised of a tandem repeat of cysteine rich zinc finger motifs and a pleckstrin domain. The C terminal region contains the catalytic domain and is distantly related to calcium regulated kinases. Catalytic activity of this enzyme promotes its

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Description

processing 5' and 3' ends of pre-tRNA precursors

The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis

where this gene has been mapped

The encoded protein contains a conserved cAMP-dependent protein kinase phosphorylation site| and plays a critical role in clustering and anchoring nicotinic acetylcholine receptors at synaptic sites by linking the receptors to the underlying postsynaptic cytoskeleton| possibly by direct association with actin or spectrin

This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells

KPCD3 Polyclonal Antibody, 100ul Drug Development and Evaluation processing 5' and 3' endsThis gene belongs to the multigene protein kinase D family of serine threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N terminal regulatory domain comprised of a tandem repeat of cysteine rich zinc finger motifs and a pleckstrin domain. The C terminal region contains the catalytic domain and is distantly related to calcium regulated kinases. Catalytic activity of this enzyme promotes its

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