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p53 Polyclonal Antibody, 50ul[BT-AP06815] Site-directed Mutagenesis The protein encoded by this

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p53 Polyclonal Antibody, 50ul[BT-AP06815] Site-directed Mutagenesis The protein encoded by thisTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

The protein encoded by this gene mediates sodium and chloride transport and reabsorption

This family member is thought to be play a role in reorganizing and regenerating the corneal matrix in granular and lattice type I dystrophies

This protein is also a co-factor for transcriptional regulation by hypoxia-inducible factor 1

The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin

The gene product is a short chain collagen and a major component of the basement membrane of the corneal endothelium

p53 Polyclonal Antibody, 50ul[BT-AP06815] Site-directed Mutagenesis The protein encoded by thisTP53 encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The tumor protein p53 responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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