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SSTR2 Polyclonal Antibody, 50ul Shaker&Mixing Mutations in DES are associated

SKU: 50514420925

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SSTR2 Polyclonal Antibody, 50ul Shaker&Mixing Mutations in DES are associatedSomatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein coupled receptors that are expressed in a tissue specific manner. SSTR2 (somatostatin receptor 2) is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney.

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Description

Mutations in DES are associated with desmin-related myopathy

and thus prevent SCAP from escorting SREBPs to the Golgi

Component of the DCX DET1-COP1 ubiquitin ligase complex at least composed of RBX1

Alternative splicing results in at least two different transcript variants

TLR9 and TRAF6

SSTR2 Polyclonal Antibody, 50ul Shaker&Mixing Mutations in DES are associatedSomatostatin acts at many sites to inhibit the release of many hormones and other secretory proteins. The biologic effects of somatostatin are probably mediated by a family of G protein coupled receptors that are expressed in a tissue specific manner. SSTR2 (somatostatin receptor 2) is a member of the superfamily of receptors having seven transmembrane segments and is expressed in highest levels in cerebrum and kidney.

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