CD55 Polyclonal Antibody, 100ul[BT-AP02140] Human Genome Knockout Libraries This gene encodes a seven-transmembrane

This gene encodes a seven-transmembrane domain protein that functions to transport cystine out of lysosomes

the exchanger may play a key role in digitalis action

Additional splicing is suggested but complete sequence for further transcripts has not been determined

Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing

and mutations in this gene have been associated with congenital chloride diarrhea

CD55 Polyclonal Antibody, 100ul[BT-AP02140] Human Genome Knockout Libraries This gene encodes a seven-transmembraneCortactin, encoded by CTTN gene (formerly EMS1), was originally identified as a substrate of the Src kinase. It is a cytoskeletal protein that interacts with F actin and Arp2 3 complex and plays an important role in regulation of actin assembly and cytoskeleton dynamics. Overexpression of cortactin increases cell migration, and is thought to contribute to the invasive phennotype of breast cancer and several other tumors. Three isoforms of cortactin