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IRF-3 Polyclonal Antibody, 50ul[BT-AP10493] Enzyme Activity Assays IQGAP3 is a Protein Coding

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SEK162.00 SEK184.00

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IRF-3 Polyclonal Antibody, 50ul[BT-AP10493] Enzyme Activity Assays IQGAP3 is a Protein CodingThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been

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Description

IQGAP3 is a Protein Coding gene

Heterogeneous nuclear ribonucleoproteins C1/C2 encoded by HNRNPC can act as a tetramer and is involved in the assembly of 40S hnRNP particles

and it is thought to mediate estrogen actions in breast cancer as a primary response gene

In a non-canonical activation pathway| the MAP3K14-activated CHUK/IKKA homodimer phosphorylates NFKB2/p100 associated with RelB| inducing its proteolytic processing to NFKB2/p52 and the formation of NF-kappa-B RelB-p52 complexes

including cell polarization and migration

IRF-3 Polyclonal Antibody, 50ul[BT-AP10493] Enzyme Activity Assays IQGAP3 is a Protein CodingThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been

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