HSP27 Polyclonal Antibody, 100ul[BT-AP04252] DNA Libraries Synthesis The protein encoded by this

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation

Act as a feedback negative regulator of signaling by receptor tyrosine kinases

Isoforms Ialpha and Ibeta have identical cGMP-bindin

and the activation of transcription factors

Hypermethylation and transcriptional downregulation of this gene has been observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q

HSP27 Polyclonal Antibody, 100ul[BT-AP04252] DNA Libraries Synthesis The protein encoded by thisHeat shock protein family B (small) member 1 encoded by HSPB1 is induced by environmental stress and developmental changes. Heat shock protein family B (small) member 1 is involved in stress resistance and actin organization and translocates from the cytoplasm to the nucleus upon stress induction. Defects in HSPB1 are a cause of Charcot Marie Tooth disease type 2F (CMT2F) and distal hereditary motor neuropathy (dHMN).