POPD1 Polyclonal Antibody, 20ul Enzymes & Activity Assays The cyclin dependent kinase inhibitor

The cyclin dependent kinase inhibitor 1B binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes

Plays an essential role in embryonic vascularization| tumor angiogenesis and pathophysiology of ischemic disease

This gene encodes a subunit of an E3 ubiquitin ligase complex that may be involved in meiosis

Lys-29 and Lys-48-linked ubiquitin chains (in vitro) (PubMed: 24724799)

The protein encoded by this gene is a member of the polo family of serine/threonine protein kinases that have a role in normal cell division

POPD1 Polyclonal Antibody, 20ul Enzymes & Activity Assays The cyclin dependent kinase inhibitorThis gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene.