NANO2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Knockout studies of a similar

Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production

Additional 5' alternatively spliced transcripts encoding the same protein have been found for the human ZIM2 gene

and piebaldism

induction:By p53/TP53

Mutations in this gene cause X-linked agammaglobulinemia type 1| which is an immunodeficiency characterized by the failure to produce mature B lymphocytes| and associated with a failure of Ig heavy chain rearrangement

NANO2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) Knockout studies of a similarThe Nanos type zinc finger is composed of two C2HC motifs, each motif binding one molecule of zinc. It is essential for the translation repression activity of the protein.,Required to support proliferation and self renewal of proximal germ cells in males only. Probably regulates translation of specific mRNAs by associating with the 3' UTR of mRNA targets. Essential for spermatogonia formation.,Belongs to the nanos family.,Contains 1 nanos type zinc