MSH2 Monoclonal Antibody, 50ul Cellular Cultivation & Health Management A similar protein in fly

A similar protein in fly functions as a tumor suppressor

LIMK1 is a serine/threonine kinase that regulates actin polymerization via phosphorylation and inactivation of the actin binding factor cofilin

Dynamin 1 like mediates mitochondrial and peroxisomal division

later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654

PubMed: 19218236

MSH2 Monoclonal Antibody, 50ul Cellular Cultivation & Health Management A similar protein in flyThis locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.