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GAS3 Polyclonal Antibody, 50ul Insect Expression In adults| higher level expression

SKU: 52199500732

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GAS3 Polyclonal Antibody, 50ul Insect Expression In adults| higher level expressionPMP22 (peripheral myelin protein 22) encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue specific expression. Various mutations of PMP22 are causes of Charcot Marie Tooth disease Type IA, Dejerine Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.

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Description

In adults| higher level expression is seen in the placenta| lung| kidney| and pancreas than in the heart| brain| liver and skeletal muscle

Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches

Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization| inositol triphosphate production and secretion of IL6 and CSF1

each case contains 500 pieces

It binds cytidine-rich sequences in double-stranded DNA

GAS3 Polyclonal Antibody, 50ul Insect Expression In adults| higher level expressionPMP22 (peripheral myelin protein 22) encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue specific expression. Various mutations of PMP22 are causes of Charcot Marie Tooth disease Type IA, Dejerine Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants.

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