Human A Disintegrin and Metalloproteinase with Thrombospondin Motifs 14, ADAMTS14 ELISA Kit, 96T Protein Post-translational Modification the first region lacks the

the first region lacks the essential Glu active site residue at position 241

Part of regulatory feedback loops in autophagy: acts both as a downstream effector and negative regulator of mammalian target of rapamycin complex 1 (mTORC1) via interaction with RPTOR (PubMed: 21795849)

It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins

This protein binds ubiquitinated lysine 63 of histone H2A and H2AX

Polymorphisms in this gene are also associated with resistance to human immunodeficiency virus type-1 infection

Human A Disintegrin and Metalloproteinase with Thrombospondin Motifs 14, ADAMTS14 ELISA Kit, 96T Protein Post-translational Modification the first region lacks the