CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays integrin alphaVbeta3

integrin alphaVbeta3

Specifically blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction

HIF-1 functions as a master regulator of cellular and systemic homeostatic response to hypoxia by activating transcription of many genes

Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED)

Alterations in the encoded protein may be associated with susceptibility to autism spectrum disorder

CYLD(Phospho-Ser418) Rabbit Polyclonal Antibody, 20ul Multiplex Immunoassays integrin alphaVbeta3This gene is encodes a cytoplasmic protein with three cytoskeletal associated protein glycine conserved (CAP GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis multiple familial trichoepithelioma and Brooke Spiegler syndrome. Alternate transcriptional splice variants encoding different isoforms have been characterized.