SLAP1 Polyclonal Antibody, 100ul Cell Function Analysis Mutations in this gene have

Mutations in this gene have been associated with susceptibility to generalized epilepsy with febrile seizures

Two transcript variants encoding different isoforms have been found for CD34

SCF(FBXO33) directs ubiquitination of YBX1 (By similarity)

Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB)

with both 4-hydroxylation and 18-hydroxylation activities

SLAP1 Polyclonal Antibody, 100ul Cell Function Analysis Mutations in this gene haveThe C terminal domain is essential for the homodimerization and the interaction with CBL. While the interaction with CBL is apparently mediated via the hydrophobic region of this domain, the highly charged region is apparently required for the homodimerization.,Adapter protein, which negatively regulates T cell receptor (TCR) signaling. Inhibits T cell antigen receptor induced activation of nuclear factor of activated T cells. Involved in the negative