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Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification Defects in this gene are

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Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification Defects in this gene areNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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Description

Defects in this gene are a cause of regulator type Rh-null hemolytic anemia (RHN)

the primary component of the cytoskeletal network

ADRA2A encodes alpha2A subtype and it contains no introns in either its coding or untranslated sequences

It uses multiple polyadenylation sites

This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5

Phospho-B23 (T199) Polyclonal Antibody, 20ul Protein Post-translational Modification Defects in this gene areNPM1 encodes a phosphoprotein which moves between the nucleus and the cytoplasm. The gene product is thought to be involved in several processes including regulation of the ARF p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in this gene are associated with acute myeloid leukemia. More than a dozen pseudogenes of NPM1 have been identified.

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