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p27(Phospho Thr157) Polyclonal Antibody, 20ul Organelle Studies while binding to the LCK

SKU: 52674971649

4.7
USD97.20 USD137.20

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p27(Phospho Thr157) Polyclonal Antibody, 20ul Organelle Studies while binding to the LCKThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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Description

while binding to the LCK SH2 domain occurs only upon TCR stimulation

may interact with and regulate the activity of this kinase

which have comparable or better specificity

Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome

A pseudogene of this gene has been defined on chromosome 5

p27(Phospho Thr157) Polyclonal Antibody, 20ul Organelle Studies while binding to the LCKThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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