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Wee 1 Polyclonal Antibody, 100ul Gene Editing Mutations associated with this gene

SKU: 52737983792

4.4
SEK123.75 SEK172.75

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Wee 1 Polyclonal Antibody, 100ul Gene Editing Mutations associated with this geneWEE1 (WEE1 G2 checkpoint kinase) encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2 cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

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Description

Mutations associated with this gene cause autosomal recessive spastic paraplegia 13

It can also induce proliferation in peripheral monocytes

Among its related pathways are Metabolism and Cytosolic iron-sulfur cluster assembly

TNS3 seems to be involved in mammary cell migration

UBE3B (ubiquitin protein ligase E3B) encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates

Wee 1 Polyclonal Antibody, 100ul Gene Editing Mutations associated with this geneWEE1 (WEE1 G2 checkpoint kinase) encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2 cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

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