PASK Polyclonal Antibody, 100ul Vessels The homodimers and heterodimers compete

The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation

Mutations in this gene cause Gitelman syndrome| a disease similar to Bartter's syndrome| that is characterized by hypokalemic alkalosis combined with hypomagnesemia| low urinary calcium| and increased renin activity associated with normal blood pressure

This gene encodes a protein that interacts with huntingtin

This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1

They play a critical role in muscle differentiation

PASK Polyclonal Antibody, 100ul Vessels The homodimers and heterodimers competeThis gene encodes a member of the serine threonine kinase family that contains two PAS domains. Expression of this gene is regulated by glucose, and the encoded protein plays a role in the regulation of insulin gene expression. Downregulation of this gene may play a role in type 2 diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.