HGK Monoclonal Antibody, 100ul[BT-MCA0674] Protein Analysis Mutations in this gene are

Mutations in this gene are the most common cause of Fanconi anemia

subunit:Interacts with DYSF

The protein contains the signature active site residues of the cysteine protease papain superfamily

This encoded protein is one of three V1 domain G subunit proteins

This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the effects of retinoic acid (RA)

HGK Monoclonal Antibody, 100ul[BT-MCA0674] Protein Analysis Mutations in this gene areThe protein encoded by this gene is a member of the serine threonine protein kinase family. This kinase has been shown to specifically activate MAPK8 JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant negative mutants of MAP3K7 TAK1, MAP2K4 MKK4, and MAP2K7 MKK7, which suggests that this kinase may function through the MAP3K7 MAP2K4 MAP2K7 kinase cascade, and mediate the TNF alpha signaling pathway. Alternatively