CR3L1 Polyclonal Antibody, 50ul Cell Transfection In addition| a polymorphic repeat

In addition| a polymorphic repeat region is found in the C-terminus of the encoded protein

This protein may act as a nuclear regulatory protein

including limb bud development

Mutations in RAD51C are associated with Fanconi anemia-like syndrome

Both proteins are widely expressed and contain an amino-terminal kinase domain followed by a central proline/serine rich domain and a highly conserved carboxy-terminal domain

CR3L1 Polyclonal Antibody, 50ul Cell Transfection In addition| a polymorphic repeatThe protein encoded by this gene is normally found in the membrane of the endoplasmic reticulum (ER). However, upon stress to the ER, the encoded protein is cleaved and the released cytoplasmic transcription factor domain translocates to the nucleus. There it activates the transcription of target genes by binding to box B elements.