Rb Polyclonal Antibody, 50ul[BT-AP07685] Peptide Library The activity of this ubiquitin

The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease

It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins

Fully programmable

This gene encodes a receptor for ephrin-B family members

Induces a cascade of intracellular signals that involves tyrosine kinase-dependent calcium mobilization| inositol triphosphate production and secretion of IL6 and CSF1

Rb Polyclonal Antibody, 50ul[BT-AP07685] Peptide Library The activity of this ubiquitinRB transcriptional corepressor 1 encoded by RB1 is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.