ARAP1 Polyclonal Antibody, 20ul Immune Repertoire Sequencing This protein also interacts with

This protein also interacts with the nuclear pore complex glycoprotein p62

Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response

Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia

glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI)

Mutations in this gene have been associated with increased severity of pseudoxanthoma elasticum

ARAP1 Polyclonal Antibody, 20ul Immune Repertoire Sequencing This protein also interacts withThe protein encoded by this gene contains SAM, ARF GAP, RHO GAP, ankyrin repeat, RAS associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3) dependent ARF GAP activity. The encoded protein associates with the Golgi, and the ARF GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell specific trafficking of a