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Raf-B Polyclonal Antibody, 100ul[BT-AP07631] Lysosome subunit:Interacts with PHB

SKU: 55173189287

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EUR123.75 EUR157.75

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Raf-B Polyclonal Antibody, 100ul[BT-AP07631] Lysosome subunit:Interacts with PHBBRAF (B Raf proto oncogene, serine threonine kinase) encodes a protein belonging to the raf mil family of serine threonine protein kinases. This protein plays a role in regulating the MAP kinase ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in BRAF are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance.

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Description

subunit:Interacts with PHB

Female mice lacking ZP2 (zona pellucida glycoprotein 2) do not form a stable zona matrix and are sterile

Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome

an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy

This protein can also interact with and activate the mitogen-activated protein kinase 14 (MAPK14/p38alpha)

Raf-B Polyclonal Antibody, 100ul[BT-AP07631] Lysosome subunit:Interacts with PHBBRAF (B Raf proto oncogene, serine threonine kinase) encodes a protein belonging to the raf mil family of serine threonine protein kinases. This protein plays a role in regulating the MAP kinase ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in BRAF are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance.

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