BRSK2 Polyclonal Antibody, 50ul Mechanical Pipette Defects in this gene may

Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE)

act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis

Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription

Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA)

Alternative splicing results in multiple transcript variants

BRSK2 Polyclonal Antibody, 50ul Mechanical Pipette Defects in this gene mayCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Thr 174 by STK11 in complex with STE20 related adapter alpha (STRAD alpha) pseudo kinase and CAB39.,Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule associated proteins.,sequence Translated as