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DNA pol Epsilon A Polyclonal Antibody, 100ul Cell Function Analysis first described as a putative

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DNA pol Epsilon A Polyclonal Antibody, 100ul Cell Function Analysis first described as a putativePOLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

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Description

first described as a putative integral membrane pentraxin that interacts with neuronal pentraxin 1 and 2

The heavy chain V region is encoded by 1 each of 3 types of genes: V genes (see MIM 147070)| joining (J) genes (see MIM 147010)| and diversity (D) genes (see MIM 146910)

OPN5 is expressed in the eye

This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells

DNA pol Epsilon A Polyclonal Antibody, 100ul Cell Function Analysis first described as a putativePOLE (DNA polymerase epsilon, catalytic subunit) encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in POLE have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature.

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