SRPK2 Polyclonal Antibody, 20ul Gene Synthesis Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding different isoforms have been observed for MOK

Mutations in this gene are associated with cerebellar ataxia

Several transcript variants encoding different isoforms| have been identified for this gene

Mutations resulting in haploinsufficiency for this gene cause familial acne inversa-2 (ACNINV2)

In migrating cells

SRPK2 Polyclonal Antibody, 20ul Gene Synthesis Multiple alternatively spliced transcript variantsCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Activated by phosphorylation on Ser 52 and Ser 588.,Phosphorylates RS domain containing proteins, such as SFRS1 and SFRS2 on serine residues. Role in spliceosome assembly and in mediating the trafficking of splicing factors. Appears to mediate HBV core protein phosphorylation which is a prerequisite for pregenomic RNA encapsidation into viral