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STRUM Rabbit Polyclonal Antibody, 100ul Roller Bottles Disruptions in the normal expression

SKU: 55805475505

4.6
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STRUM Rabbit Polyclonal Antibody, 100ul Roller Bottles Disruptions in the normal expressionThis gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin repeat containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive lower

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Description

Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer

but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited

and small intestine

|PTM:Phosphorylated by cyclin A/CDK2

TPases are a group of enzymes that catalyze hydrolysis of the gamma phosphate bond in guanine triphosphate (GTP) to form guanine diphosphate (GDP)

STRUM Rabbit Polyclonal Antibody, 100ul Roller Bottles Disruptions in the normal expressionThis gene encodes a 134 kDa protein named strumpellin that is predicted to have multiple transmembrane domains and a spectrin repeat containing domain. This ubiquitously expressed gene has its highest expression in skeletal muscle. The protein is named for Strumpell disease; a form of hereditary spastic paraplegia (HSP). Spastic paraplegias are a diverse group of disorders in which the autosomal dominant forms are characterized by progressive lower

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