Rat Macrophage Inflammatory Protein 1Α, MIP1A ELISA Kit, 96T Enzymes Guanine nucleotide exchange factor (GEF)

Guanine nucleotide exchange factor (GEF) which may activate RAB8A and RAB8B

required for the functional interaction of kinesin I with axonal cargo

which are enzymes involved in cellular responses to oxidative stresses and irradiation

The LIM/double zinc-finger motif found in this gene product occurs in proteins with critical functions in gene regulation

25% Trypsin

Rat Macrophage Inflammatory Protein 1Α, MIP1A ELISA Kit, 96T Enzymes Guanine nucleotide exchange factor (GEF)Monokine with inflammatory and chemokinetic properties. Has chemotactic activity for monocytes, neutrophils, eosinophils, basophils, and lymphocytes. Required for lung TNF alpha production, neutrophil recruitment and subsequent lung injury and may function as an autocrine mediator for the macrophage production of TNF alpha which in turn up regulates vascular adhesion molecules required for neutrophil influx. This protein binds heparin.