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Rpb1(Phospho Ser1619) Polyclonal Antibody, 50ul Micro Centrifuge Tubes RARRES3 is thought act as

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Rpb1(Phospho Ser1619) Polyclonal Antibody, 50ul Micro Centrifuge Tubes RARRES3 is thought act asThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase

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Description

RARRES3 is thought act as a tumor suppressor or growth regulator

and carcinogenesis

Mutations in this gene cause Griscelli syndrome type-1 (GS1)

An important paralog of this gene is GPR137B

Proteins in this family are part of the ESCRT-III (endosomal sorting complex required for transport III) which degrades surface receptors

Rpb1(Phospho Ser1619) Polyclonal Antibody, 50ul Micro Centrifuge Tubes RARRES3 is thought act asThis gene encodes the largest subunit of RNA polymerase II the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition this subunit in combination with several other polymerase

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