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TRAP240 Polyclonal Antibody, 50ul[BT-AP09182] Peripheral Blood Separation Tube a leukocyte-specific adaptor protein important

SKU: 56485331583

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TRAP240 Polyclonal Antibody, 50ul[BT-AP09182] Peripheral Blood Separation Tube a leukocyte-specific adaptor protein importantMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.

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Description

a leukocyte-specific adaptor protein important for immune cell signaling

The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane

indicating a potential role in transcriptional regulation

Alternative splicing of PAX2 results in multiple transcript variants

PTM:Phosphorylated on tyrosine residues upon TCR or BCR activation

TRAP240 Polyclonal Antibody, 50ul[BT-AP09182] Peripheral Blood Separation Tube a leukocyte-specific adaptor protein importantMED13 (mediator complex subunit 13) encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre initiation complex.

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