Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 50ul Serum a pseudogene of SRSF11 has

a pseudogene of SRSF11 has been found on chromosome 12

Expression of this gene is highly restricted

class II and class III

The N-terminus is poorly conserved and may impart additional roles in developmental regulation

this enzyme may be involved in such varied processes as gluconeogenesis

Tuberin/TSC2(Phospho-Ser1254) Rabbit Polyclonal Antibody, 50ul Serum a pseudogene of SRSF11 hasMutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.