MFN1 Rabbit Polyclonal Antibody, 50ul Gene Synthesis EPN1 encodes a member of

EPN1 encodes a member of the epsin protein family

The encoded type II transmembrane protein interacts with dnax-activation protein 12 and may play a role in cell activation

This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5

Under hypoxic conditions activates the transcription of over 40 genes| including| erythropoietin| glucose transporters| glycolytic enzymes| vascular endothelial growth factor| and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia

The membrane protein is a calcium-dependent receptor that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes

MFN1 Rabbit Polyclonal Antibody, 50ul Gene Synthesis EPN1 encodes a member ofThe protein encoded by this gene is a mediator of mitochondrial fusion. This protein and mitofusin 2 are homologs of the Drosophila protein fuzzy onion (Fzo). They are mitochondrial membrane proteins that interact with each other to facilitate mitochondrial targeting.