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BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos this protein is sometimes secreted

SKU: 5771205827

4.3
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BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos this protein is sometimes secretedBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

this protein is sometimes secreted

Multiple alternatively spliced transcript variants encoding the same protein are observed

with biallelic

which contains a trinucleotide repeat (CAG) length polymorphism

an bind to the surface of B-lymphoma cells

BRCA1 Polyclonal Antibody, 50ul[BT-AP00966] Diagnostic Probes & Oligos this protein is sometimes secretedBRCA1encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein (BRCA1, DNA repair associated) combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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