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CD172b Polyclonal Antibody, 100ul Lysosome An important paralog of this

SKU: 5787260220

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CD172b Polyclonal Antibody, 100ul Lysosome An important paralog of thisSignal regulatory protein beta 1 encoded by SIRPB1 is a member of the signal regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase coupled signaling processes. This protein was found to interact with TYROBP DAP12, a protein bearing immunoreceptor tyrosine based activation motifs.

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Description

An important paralog of this gene is RPA4

Mutations in NT5C3A are a cause of hemolytic anemia due to uridine 5-prime monophosphate hydrolase deficiency

Interacts with phosphorylated proteins ZAP70

LMWK is not involved in blood coagulation

Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome

CD172b Polyclonal Antibody, 100ul Lysosome An important paralog of thisSignal regulatory protein beta 1 encoded by SIRPB1 is a member of the signal regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase coupled signaling processes. This protein was found to interact with TYROBP DAP12, a protein bearing immunoreceptor tyrosine based activation motifs.

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