Cytokeratin 8(Phospho Ser432) Polyclonal Antibody, 20ul Immuno Plates This protein has been found

This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB

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In mouse an alternatively spliced form of this protein has been shown to act as a cytokine and can induce the production of the inflammatory cytokine IL6 in osteoblasts

spinal muscular atrophy

Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system

Cytokeratin 8(Phospho Ser432) Polyclonal Antibody, 20ul Immuno Plates This protein has been foundThis gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal