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ASC-1 Polyclonal Antibody, 100ul Centrifuges A translocation event between this

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ASC-1 Polyclonal Antibody, 100ul Centrifuges A translocation event between thisTRIP4 (thyroid hormone receptor interactor 4) encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC 1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors mediated transcription. This protein is localized in the nucleus and contains an E1A type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand

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Description

A translocation event between this gene and Notch coactivator mastermind-like gene 2

shown here

The active| hypophosphorylated form of the protein binds transcription factor E2F1

The encoded protein has been shown to undergo autophosphorylation

Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness

ASC-1 Polyclonal Antibody, 100ul Centrifuges A translocation event between thisTRIP4 (thyroid hormone receptor interactor 4) encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC 1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors mediated transcription. This protein is localized in the nucleus and contains an E1A type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand

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