CCL22 Rabbit Polyclonal Antibody, 20ul[BT-AP07339] Microplate Mixer exon 4 encodes the transmembrane

exon 4 encodes the transmembrane domain and the cytoplasmic tail

It has an N-terminal short-chain dehydrogenase domain with a cofactor binding site

This gene encodes a secreted protein with a cystein-knot motif that activates the Wnt/beta-catenin pathway

and defective DNA repair

Defects in the gene encoding ZFYVE19 are associated with acute myeloblastic leukemia (AML)

CCL22 Rabbit Polyclonal Antibody, 20ul[BT-AP07339] Microplate Mixer exon 4 encodes the transmembraneMay play a role in the trafficking of activated effector T lymphocytes to inflammatory sites and other aspects of activated T lymphocyte physiology. Chemotactic for monocytes dendritic cells and natural killer cells. Mild chemoattractant for primary activated T lymphocytes and a potent chemoattractant for chronically activated T lymphocytes but has no chemoattractant activity for neutrophils eosinophils and resting T lymphocytes. Binds to CCR4.