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SNPC3 Polyclonal Antibody, 20ul Organelle Studies This gene encodes a member

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SNPC3 Polyclonal Antibody, 20ul Organelle Studies This gene encodes a memberPart of the SNAPc complex required for the transcription of both RNA polymerase II and III small nuclear RNA genes. Binds to the proximal sequence element (PSE), a non TATA box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3

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Description

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET

It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates

while expression is weak to moderate in astrocytomas

The protein encoded by RECK (reversion inducing cysteine rich protein with kazal motifs) is a cysteine-rich

and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin

SNPC3 Polyclonal Antibody, 20ul Organelle Studies This gene encodes a memberPart of the SNAPc complex required for the transcription of both RNA polymerase II and III small nuclear RNA genes. Binds to the proximal sequence element (PSE), a non TATA box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box.,PTM: Phosphorylated upon DNA damage, probably by ATM or ATR.,subunit: Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3

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