IRS-1 Polyclonal Antibody, 100ul[BT-AP04645] Lysosome APPBP2 has been found to

APPBP2 has been found to be highly expressed in breast cancer

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity

Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system

since the encoded protein upregulates the tumor suppressor p53

The encoded protein plays a critical role in cell proliferation

IRS-1 Polyclonal Antibody, 100ul[BT-AP04645] Lysosome APPBP2 has been found toIRS1 encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.