53BP1 Polyclonal Antibody, 20ul[BT-AP00040] ROS/Nitric Oxide Detection The ADAM metallopeptidase with thrombospondin

The ADAM metallopeptidase with thrombospondin type 1 motif 7 encoded by ADAMTS7 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family

but it is expressed in hematopoietic tissues and appears to be restricted to primitive stem cells present in those tissues with functions in blood and vessel development

These cells were also positive for the marker CD133

Comes with an individually packaged centrifuge tube cap for easy storage

Diseases associated with ACOT1 include human immunodeficiency virus infectious disease

53BP1 Polyclonal Antibody, 20ul[BT-AP00040] ROS/Nitric Oxide Detection The ADAM metallopeptidase with thrombospondinThe p53 binding proteins 53BP1 and 53BP2 (Bbp) bind to the central DNA binding domain of wild type p53, but do not bind mutant p53. The central DNA binding domain of p53 is required for site specific DNA binding and is frequently mutated in malignant tumors. Binding of 53BP1 to the L3 loop of p53 and of 53BP2 to the L2 loop of p53 confirms that the loop is dependent on p53 conformation. Site specific binding also suggests that 53BP1 and 53BP2 are