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Phospho-Bax (S184) Polyclonal Antibody, 100ul Microbial Genome Editing Mutations in EGFR are associated

SKU: 5913959489

4.8
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Phospho-Bax (S184) Polyclonal Antibody, 100ul Microbial Genome Editing Mutations in EGFR are associatedThe protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage dependent anion

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Description

Mutations in EGFR are associated with lung cancer

The encoded protein contains an N-terminal actin-binding domain

The encoded protein localizes to cell membranes and is required for zinc uptake in the intestine

They negatively regulate members of the MAP kinase superfamily

thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm

Phospho-Bax (S184) Polyclonal Antibody, 100ul Microbial Genome Editing Mutations in EGFR are associatedThe protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero or homodimers and act as anti or pro apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage dependent anion

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