Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology Knockout studies in mice suggest

Knockout studies in mice suggest that the different receptors

It has an altered intracellular processing and is trapped within the endoplasmic reticulum

involved in late-phase long-term potentiation (L-LTP) maintenance at the Schaffer collateral-CA1 synapses

where carcinogen-induced damage can lead to translocations and aberrant transcripts of this gene

Related pseudogenes have been found on chromosomes 3 and 14

Phospho-BLNK (Y96) Polyclonal Antibody, 50ul Cell Biology Knockout studies in mice suggestBLNK encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. B cell linker bridges B cell receptor associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia