DBLOH Polyclonal Antibody, 50ul Filtration Alternative translation initiation site usage

Alternative translation initiation site usage results in the production of different isoforms (PMID:12105216)

DZIP3 (DAZ Interacting Zinc Finger Protein 3) is a Protein Coding gene

alpha2(VI)

and also associates with eukaryotic initiation factor 4E-binding protein-1 and ribosomal protein S6 kinase

This gene contains at least 14 exons| and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons

DBLOH Polyclonal Antibody, 50ul Filtration Alternative translation initiation site usageThis gene encodes an inhibitor of apoptosis protein (IAP) binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young adult onset of nonsyndromic deafness 64. Alternative splicing results in multiple transcript