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Abl1 Polyclonal Antibody, 50ul[BT-AP00132] Microplate Mixer Polymorphisms in this gene may

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Abl1 Polyclonal Antibody, 50ul[BT-AP00132] Microplate Mixer Polymorphisms in this gene mayABL1 is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein (ABL proto oncogene 1, non receptor tyrosine kinase)is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is

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Description

Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders

Mutations in this gene are a cause of hypomyelinating leukodystrophy

Homotetramers consisting of a proteolytically cleaved form of the protein| or type A subunit| exhibit low affinity for heparin and do not interact with the ECM

This gene encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin)

Anti-apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli

Abl1 Polyclonal Antibody, 50ul[BT-AP00132] Microplate Mixer Polymorphisms in this gene mayABL1 is a protooncogene that encodes a protein tyrosine kinase involved in a variety of cellular processes, including cell division, adhesion, differentiation, and response to stress. The activity of the protein (ABL proto oncogene 1, non receptor tyrosine kinase)is negatively regulated by its SH3 domain, whereby deletion of the region encoding this domain results in an oncogene. The ubiquitously expressed protein has DNA binding activity that is

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