KLHL12 Monoclonal Antibody, 100ul Plates & Dishes AVEN expression may be a
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KLHL12 Monoclonal Antibody, 100ul Plates & Dishes AVEN expression may be aThis gene encodes a member of the KLHL (Kelch like) family of proteins. This protein has been identified as an autoantigen in the autoimmune disease Sjogren's syndrome and as a potential biomarker in primary biliary cirrhosis. This protein may act as a substrate adaptor of the Cullin 3 ubiquitin ligase complex to promote substrate specific ubiquitylation. Ubiquitylation by this complex has been shown to regulate the Wnt signaling pathway as well as
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