TNF Alpha-IP 2 Polyclonal Antibody, 20ul Roller Bottles FERM RhoGEF and pleckstrin domain-containing

FERM RhoGEF and pleckstrin domain-containing protein 2 functions as guanine nucleotide exchange factor that activates RAC1

precerebellins do not contain a collagen motif

Pseudogenes corresponding to this gene are found on chromosomes 1p

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The protein encoded by FKBPL (FK506 binding protein like) has similarity to the immunophilin protein family

TNF Alpha-IP 2 Polyclonal Antibody, 20ul Roller Bottles FERM RhoGEF and pleckstrin domain-containingTNFAIP2 (TNF alpha induced protein 2) was identified as a gene whose expression can be induced by the tumor necrosis factor alpha (TNF) in umbilical vein endothelial cells. The expression of TNFAIP2 was shown to be induced by retinoic acid in a cell line expressing a oncogenic version of the retinoic acid receptor alpha fusion protein, which suggested that TNFAIP2 may be a retinoic acid target gene in acute promyelocytic leukemia.